Endocrine Abstracts

Introduction: Inadequate glucocorticoid replacement therapy in Addison disease leads to an increased risk of both cardiovascular disease and metabolic syndrome. The metabolic effects of long-life corticosteroid exposure are due to physiological mechanisms that are associated with carbohydrate metabolism disorder, dyslipidemia and insulin resistance. In this study, we aimed to determine the prevalence and predictive factors of metabolic syndrome in patients with Addison disease...

Background and Aims: Growing scientific evidence supports the hypothesis of an increased cardiometabolic risk in patients harboring adrenal incidentalomas (AI). This risk would be higher in aging populations and patients with functioning adenomas. The current study aims to determine the clinical and biochemical characteristics of metabloic syndrome(MetS) and assess its prevalence in older patients with AI.Patients and Method: We conducted a retrospective...

Background and Aims: Arterial hypertension (AH) is one of the most common comorbidities in the elderly. The association of adrenal incidentaloma (AI) with AH in older patients may influence the clinical and therapeutic outcomes of the latter condition. In the current study, we aimed to assess the prevalence of AH and its clinical and therapeutic features in geriatric patients bearing AI.Patients and Method: We conducted a retrospective descriptive study ...

Introduction: Conventional glucocorticoid replacement therapy has been suggested to increase morbidity in patients with Addison disease and fail to restore their quality of life (QOL). The aim of our study was to assess QOL in patients with Addison disease and to identify factors that determine their QOL.Patients and methods: This cross-sectional study was carried out at the department of Endocrinology in HediChaker hospital-Sfax –Tunisia, from Marc...

Introduction: Patients with Addison disease require lifelong glucocorticoid replacement treatment and it is recommended that glucocortiocoid therapy should be monitored in these patients to avoid over replacement and minimize long-term consequences of bone loss. The present study was carried out with the aim of evaluating bone turnover markers in patients with Addison disease.Patients and methods: A cross sectional study including 50 patients who are fol...

Introduction: Because of a long-term glucocorticoid replacement over many years, patients with Addison disease may have an increased occurrence of osteoporosis. Furthermore, the prevalence of osteoporosis in patients with Addison disease may also be increased because of premature menopause associated autoimmune endocrinopathies and hypovitaminosis D.The objective of this study is to assess the incidence and risk factors for osteoporosis among patients with Addison disease....

Introduction: Even at physiological doses, glucocorticoid replacement therapy may lead to deleterious outcomes on bone mineral density (BMD).The aim of our study was to investigate the BMD in Tunisian patients with Addison disease and to identify the risk factors associated with its decline.Patients and methods: The study included 50 patients diagnosed with primary adrenal disease (Addison disease). BMD was assessed by the dual -energy -X-ray absopitomet...

Introduction: Obesity is a global epidemic with a growing prevalence in recent decades. In Tunisia, obesity is a major problem as it is increasing in adults as well as in children and adolescents. It therefore appears important to deepen the knowledge on this pathology and especially on the psychological profile, since studies concerning the mental health of obese subjects remain rare.Purpose: Study the psychological impact of obesity in adult women<...

Introduction: Hypothyroidism has always been considered one of the most common endocrine etiologies of obesity. That said, would screening for hypothyroidism be justified in the face of obesity? The purpose of our study was to study the thyroid profile of obese people.Patients and methods: We conducted a retrospective study which patients with obesity hospitalized in the diabetology endocrinology department, CHU Hédi Chaker of Sfax, between 01/10/20...

Introduction: Diabetes mellitus is a major public health problem affecting all ages worldwide. In Tunisia, 18% of the population has diabetes mellitus. In fact, it is one of the first ten causes of death in our country.Therefore, self-management education for diabetic patients play an important role in reducing diabetes complications and mortality rate. The education is conducted not only by doctors, but also by nurses.Purpose: The aim of this study is t...